Changes in functioning of the dopamine receptors that controls the reward/reinforcement center of our brains can be passed our progeny after just one or two episodes of drug use, heightening their chances of having addiction issues, according to new research. The field of epigenetics is the study of inheritied changes in appearance or gene expression caused by mechanisms other than changes in the underlying DNA. Dr Inaba expands on the topic. We also continue our discussion of the steadily increasing abuse and increasing number of deaths and ER visits resulting from misuse of prescription drugs.